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Under These Conditions, IgA Nephropathy Patients Should Reject Taking Steroids

Under These Conditions, IgA Nephropathy Patients Should Reject Taking SteroidsSteroids have long been the drug of choice for chronic kidney disease. However, nearly half of the patients with nephritis have IgA Nephropathy. In general, glucocorticoid therapy will be used if their 24-hour urine protein reaches 1g.

But the side effect of hormone is very serious, then should you eat it or not?

A global study on glucocorticoid therapy for IgA nephropathy

In 2012, researchers selected 500 IgA nephropathy patients from 70 hospitals around the world and divided them into two groups: one was treated with methylprednisolone and the other was routinely treated with antihypertensive drugs.

Two years later, 20 of the patients in the hormone group had serious adverse reactions (including death), five times more than in the non-hormone group.

Hormone treatment for IgA nephropathy can help reduce proteinuria, but will greatly increase the risk of infection, or even the occurrence of fatal infection.

When the 24-hour urine protein of the patients is about 1g or so, the harm of taking hormone is bigger than that of urine protein! If the treatment of urinary protein is to bring greater harm to the body, that is really not worth the loss!

So how does the patient know whether he/she is IgA nephropathy or not?

1. The urine protein is between 4000 and 10000;

2. Glomerular erythrocytes (abnormal erythrocytes > 60%, deformed erythrocyte shapes >= 3, spinous erythrocytes > 5%);

3. IgA>3.15,IgA/C3>3.01;

4. The pathological findings of renal biopsy show that the glomerular mesangial cells and matrix are mainly increased, and immunofluorescence was the diffuse deposition of pure lgA or lgA-based immunoglobulin in the glomerular mesangial area and capillary loop.

If you have most (or even all) of them, you are almost certainly suffering from IgA Nephropathy. At this point, if your 24h urine protein is 1g, and your doctor prescribes steroids, you can say no to him/her.

If you reject steroids, how to treat the disease?

The optimal level of proteinuria control in patients with IgA Nephropathy is: 24-hour urinary protein quantification less than 0.5g.

To achieve this level, it is necessary to use traditional Chinese medicine combined with umbilical therapy and other methods to promote kidney and blood circulation, dispel wind and clear collaterals, increase blood microcirculation so as to clean up a large amount of stored abnormal glycosylation of IgA1 and its immune complexes in the blood, repair the damaged parts of the glomeruli so that protein, occult blood and so on won’t leak out of the kidneys.

Note:the above material is intended for informational purposes. For specific suggestions, please consult a physician.

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Hope the above information is helpful for you. If you have any other questions on kidney disease or want to get more personalized and professional treatment suggestions, please leave a message below.

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